Ubiquinone and Ubiquinol are the two main types of CoQ10. The body needs both types and will convert Ubiquinone to Ubiquinol naturally via an enzymatic conversion process, depending on which form is needed at the time. This conversion occurs automatically unless you are in the minority group of people who have a genetic mutation /polymorphism causing a lack of the enzymes necessary to make the conversion and therefore need to take both Ubiquinone and Ubiquinol. However, the majority of people do not have this issue.
CoQ10 naturally shifts back and forth between its ubiquinone and its ubiquinol form in a continuous cycle inside the body, depending on which type is needed at the time. For example, in the blood and lymph; CoQ10 primarily serves as an antioxidant, but in the mitochondria it supports the energy metabolism by switching between the two forms back and forth many times per second. When you take ubiquinol, it changes to ubiquinone & vice versa. It makes no difference which form you take initially unless you have a conversion problem as mentioned above, but most people do not.
Ubiquinone is more stable, the most studied, proven and less expensive. Ubiquinone has been used in the vast majority of studies. Thousands of clinical trials have been conducted with Ubiquinone, only a few have been conducted with ubiquinol. The majority of research has been carried out with ubiquinone. The most recent study of Ubiquinone showed a 43% lower risk for heart-related mortality among heart failure patients who took Ubiquinone supplements. In this study (the Q-Symbio clinical trial), ubiquinone only was used. Another study (the KiSel-10 clinical trial), which was published nearly two years ago and which showed a 54% lower mortality rate among elderly people who took supplements of CoQ10 (and selenium) was also conducted with ubiquinone.
The renowned Cardiologist, Dr. Sinatra MD, did a comparison of the two forms of CoQ10 with his patients and he said: "I performed an informal 12-person study. Half of the participants took 200 mg of ubiquinol and the other half took 200 mg of ubiquinone for the first month. In the third month, the participants switched to the other form of CoQ10. I checked the participants’ coenzyme Q10 blood levels each month and found that both groups achieved excellent results, with ubiquinol resulting in only slightly higher blood levels of CoQ10—making it NOT WORTH the much higher cost. Plus, for one participant ubiquinol resulted in a significantly lower coenzyme Q10 blood level when compared to ubiquinone. More importantly, I was disturbed by feedback from one volunteer who complained of fatigue when she took ubiquinol. I also heard similar complaints of fatigue from two respected colleagues who are nutrition experts. By contrast, the usual feedback I hear from people taking ubiquinone is that they feel they have more energy, not less."
Ubiquinol is susceptible to oxidation and when it oxidizes, it converts back into ubiquinone. The marketing hype for ubiquinol being superior have left many people confused about which form to trust. Since the different forms of CoQ10 can easily be converted from one form to the other, it makes sense to stick with the form that is more affordable. Ubiquinol is much more expensive and tends to convert back into ubiquinone in the capsule anyway from oxidation.
1) The number of scientific studies conducted with ubiquinone is far greater than the studies carried out with ubiquinol
2) In terms of absorption, there is no documented difference between ubiquinol & ubiquinone
3) Ubiquinone and ubiquinol convert back and forth from one form to the other inside the body, as needed at any given moment.
4) Ubiquinone is the #1 recommended type by cardiologists and primary care doctors.
5) Ubiquinol is unstable and much more expensive. The best way to find out what works personally for you is to try both, one at a time, and see which form you feel better on and which one raises your CoQ10 levels better. We recommend you start with Ubiquinone first as this is sufficient for most people.
Most other CoQ10 supplements on the market are derived from tobacoo and synthetic, hence their much lower cost. Our Ubiquinone is naturally fermented and bio-identical, which means it's in the same form the body produces at a young age, which increses bioavailability and efficacy. In addition, since CoQ10 is fat soluble and better absorbed when taken with fats, our Coq10 is formulated in a suspension of organic olive oil and sunflower lecithin in a softgel for maxium absoprtion. This means you can take our CoQ10 at anytime, even on an empty stomach away from food and still get the highest absorbption. Or it can be taken with a meal, if you prefer, but it's not neccessary like with other CoQ10 supplements.
Check out our Customer Reviews and you can see the results speak for themselves! Try our COQ10 today 100% Risk free!